Lake Lucerne (Vierwaldstättersee) is a lake in Switzerland.

Lake Lucerne or Lake Luzerne may also refer to:

Lakes Lake Lucerne (California) Lake Lucerne (Polk County, Florida), a small lake north of Winter Haven Lake Luzerne (New York) Lake Lucerne (Wisconsin) Pipe Lake-Lake Lucerne two connected lakes in Washington

Communities Lake Lucerne, Florida, neighborhood in Miami Gardens Lake Luzerne, New York, a town Lake Luzerne (CDP), New York, hamlet within the town

See also Lucerne (disambiguation)