Tropatepine (brand name Lepticur) is an anticholinergic used as an antiparkinsonian agent.
Synthesis Tropatepine can be synthesized from 3-chlorotropane (1).DE1952206 idem J Boissier, R Ratouis, (1973 to Ind Pour La Fab Antibiotiques). A Grignard reaction between 3-chlorotropane and dibenzo[b,e]thiepin-11(6H)-one (2) followed by dehydration to the olefin produces tropatepine (3).
See also Muscarinic antagonist
References