CUC may refer to:

Education Canadian University College, a private Seventh-day Adventist degree-granting institution and teacher's college in Lacombe, Alberta, Canada Catholic University College, Kensington, a 19th Century college of higher education Ciudad Universitaria de Caracas, the Spanish name of University City of Caracas, a World Heritage Site and the college campus of Universidad Central de Venezuela Claremont University Consortium, a group of seven colleges in California, USA Columbia Union College, a former name of Washington Adventist University, a liberal arts university located in Takoma Park, Maryland, USA Combined Universities in Cornwall, a project to provide higher education in Cornwall, UK Communication University of China, a university in Beijing, China Concordia University Chicago, a private Lutheran university in River Forest, Illinois, USA

Organisations Canadian Unitarian Council, the national body for Unitarian Universalist congregations in Canada Canadian Unity Council, a former non-profit organization whose mission was the promotion of Canadian unity Caribbean Utilities, a utilities company based in the Cayman Islands Comité de Unidad Campesina, the Spanish name for the former Committee for Peasant Unity in Guatemala CUC Broadcasting, a former Canadian media company CUC International, a former consumer services conglomerate involved in a 1998 accounting scandal CUC Software (now Vivendi Games), the software unit of CUC International

Other Canadian Ultimate Championships, a national tournament of Ultimate in Canada Cuban convertible peso, formerly one of two official currencies in Cuba, by ISO 4217 code CUC, the IATA airport code for Camilo Daza International Airport, Cúcuta, Colombia CUC, codon for the amino acid leucine