Melanoides nyassana is a species of freshwater snail with a gill and an operculum, an aquatic gastropod mollusc in the family Thiaridae.

It is endemic to Lake Malawi, where it is widespread.

Melania truncatelliformis Bourguignat, 1889 may be a synonym of Melanoides nyassana.Brown D. S. (1994). Freshwater Snails of Africa and their Medical Importance. Taylor & Francis. . The IUCN Red List of Threatened Species treats the species as a synonym of Melanoides polymorpha.

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