5S may refer to:
5S (methodology), a Japanese management methodology 5S ribosomal RNA Select Society of Sanitary Sludge Shovelers A series of Toyota S engines A technique for calming babies, as suggested by Harvey Karp iPhone 5S, a smartphone by Apple Inc. 5S, the production code for the 1981 Doctor Who serial Warriors' Gate Fives, an English sport
See also S5 (disambiguation) 5 (disambiguation)