Iannucci is an Italian surname. Notable people with the surname include:
Antonio Iannucci (1914–2008), Italian prelate of the Roman Catholic Church Armando Iannucci (born 1963), Scottish comedian, writer, director, performer, and radio producer Athan Iannucci (born 1982), professional lacrosse player Robert Iannucci (born 1955), American computer scientist