QWK may refer to:
every week, medication dosage term QWK (file format), used by offline mail readers WLEJ (AM) 1450 AM, "QWK" Rock, radio station broadcasting from State College, Pennsylvania, USA WQWK (FM) 105.9 FM, which also carries the QWK brand in State College, Pennsylvania, USA WOWY (FM) 103.1 FM, a defunct station of State College, Pennsylvania, USA