José Hernández may refer to:
Arts and entertainment Jose Acosta Hernandez (born 1966), Cuban-born American artist José Hernández (writer) (1834–1886), Argentine writer Pepe Hern (José Hernández Bethencourth, 1927–2009), American actor José Hernández, American singer (born 1940), better known as Little Joe José Hernández (painter) (1944–2013), Spanish painter José Hernández (musician) (born 1958), Mexican musician Chef Pepín (José Hernández), Cuban-born, American TV cook José Hernández Delgadillo (1927–2000), Mexican painter and muralist
Politicians José Conrado Hernández (1849–1932), Chief Justice of the Supreme Court of Puerto Rico José Manuel Hernández (1853–1921), Venezuelan caudillo, army general and politician José Alarcón Hernández (born 1945), Mexican politician José María Hernández (1959–2015), Spanish politician José Hernández Concepción, Puerto Rican politician
Science and academia José Gregorio Hernández (1864–1919), Venezuelan physician José M. Hernández (born 1962), American astronaut José Hernández-Rebollar (born 1969), Mexican engineer
Sportspeople Association football Cheche Hernández (born 1956), Colombian manager José Hernández (footballer, born 1961), Venezuelan manager and former footballer José Alberto Hernández (born 1977), Mexican football midfielder José Hernández (footballer, born 1994), Mexican midfielder José Romario Hernández (born 1994), Mexican winger José Hernández (footballer, born April 1996), Mexican midfielder José Hernández (footballer, born August 1996), Venezuelan winger for Caracas José Hernández (footballer, born 1997), Venezuelan left-back for La Equidad José Santiago Hernández (born 1997), Mexican goalkeeper José Hernández (soccer, born 2000), Canadian forward
Baseball José Hernández (infielder) (born 1969), Puerto Rican baseball player José Hernández (pitcher) (born 1997), Dominican baseball player Cheo Hernández (José Hernández, 1894–?), Negro leagues pitcher
Other sports José Carlos Hernández (born 1978), Spanish long-distance runner José Hernández (handballer) (born 1979), Cuban handball player José Hernández-Fernández (born 1990), Dominican Republic tennis player José Tito Hernández (born 1995), Colombian road cyclist
Other uses José María Hernández González (1927–2015), Catholic bishop José Hernández (Buenos Aires Underground), a metro station in Buenos Aires