Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core.
5β-Pregnane is the parent of pregnanediones, pregnanolones, and pregnanediols, and is found largely in urine as a metabolic product of 5β-pregnane compounds.
Pregnanes
Pregnanes are steroid derivatives with carbons present at positions 1 through 21.
Most biologically significant pregnane derivatives fall into one of two groups: pregnenes and pregnadienes. Another class is pregnatrienes.
Pregnenes
Pregnenes have a double bond. Examples include: Cortisone Hydrocortisone Progesterone
Pregnadienes
Pregnadienes have two double bonds. Examples include: Cyproterone acetate Danazol Fluocinonide
See also 5β-Pregnane Pregnanedione Pregnanediol 19-Norpregnane Androstane Estrane
References
External links
PubChem Diagram at qmul.ac.uk Definition of Pregnane Progesterone Chemistry Progesterone record in European Bioinformatics database