Polyaminopropyl biguanide (PAPB) is a polymer containing biguanide group connected with a three methylene (propyl) linker. The polymer is a propyl analogue of polyhexamethylene biguanide. The polymer displays some antibacterial activity, although much lower than PHMB.Rembe, J.-D., Fromm-Dornieden, C., Schafer, N., Böhm, J. K., & Stuermer, E. K. (2016). Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide. *Journal of Medical Microbiology*, 65(8), 867 As of May 2024, PAPB is not approved as a biocidal active substance under EU regulations. European Chemicals Agency (ECHA). (n.d.). List of approved active substances. Retrieved May 24, 2024, from https://echa.europa.eu/regulations/biocidal-products-regulation/approval-of-active-substances/list-of-approved-active-substances
Name controversy In some sources, particularly in lists of cosmetic ingredients (INCI), the name polyaminopropyl biguanide is wrongly associated with polyhexamethylene biguanide (PHMB)
References