Edward Stafford may refer to:
People Edward Stafford, 2nd Earl of Wiltshire (1470–1498) Edward Stafford, 3rd Duke of Buckingham (1478–1521), executed for treason Edward Stafford, 3rd Baron Stafford (1535–1603) Sir Edward Stafford (diplomat) (1552–1605), English ambassador to Paris and MP Edward Stafford, 4th Baron Stafford (1572–1625) Sir Edward Stafford (politician) (1819–1901), Premier of New Zealand Ed Stafford (born 1975), British explorer Edward Stephen Stafford, editor of The Johns Hopkins Medical Journal
Fictional characters Edward Stafford (The Tudors), a fictionalized version of the 3rd Duke of Buckingham, on the TV show "The Tudors"
See also Stafford (surname)