Jean-François () is a French given name. Notable people bearing the given name include:
Jean-François Carenco (born 1952), French politician Jean-François Champollion (1790–1832), French Egyptologist Jean-François Clervoy (born 1958), French engineer and astronaut Jean-François Corminboeuf (born 1953), Swiss sport sailor Jean-François Coulomme (born 1966), French politician Jean-François Dagenais (born 1975), Canadian music producer Jean-François David (born 1982), Canadian ice hockey player Jean-François Gariépy (born 1984), Canadian alt-right political commentator and former neuroscientist Jean-François Garreaud (1946–2020), French actor Jean-François de La Harpe (1739–1803), French critic Jean-François Hernandez (born 1969), French football player Jean-François Larose (born 1972), Canadian politician Jean-François Lyotard (1924–1998), French philosopher Jean-François Marceau (born 1976), Canadian judoka Jean-François Marmontel (1723–1799), French historian and writer Jean-François Martial (1891–1977), Belgian actor Jean-François Mayer (born 1957), Swiss historian of religion Jean-François Mertens (1946-2012), Belgian mathematical economist Jean-François Millet (1814–1875), French painter Jean-François Ndongou (born 1960), Gabonese politician Jean-François Papillon (died 1805), Haitian revolutionary Jean-François Parigi (born 1960), French politician Jean-François Picheral (1934–2024), French politician Jean-François Racine (born 1982), Canadian ice hockey player Jean-François Rewbell (1747–1807), French politician Jean-François Ricard (born 1956), French prosecutor of the National Terrorism Prosecution Office for the prosecution of terrorism in France Jean-François Rousset (born 1952), French politician Jean-François Séguier (1703–1784), French astronomer and botanist
See also Jean-François, comte de Durat (1736–1830), French noble and military officer Jean L. François (1882–1941), French philatelist Jean-François, blue rabbit-cat hybrid from the TV series Bunny Maloney