John Little may refer to:
Politics John Little (congressman) (1837–1900), U.S. Representative from Ohio John Sebastian Little (1851–1916), U.S. Representative from Arkansas John William Little, Canadian politician John Fletcher Little (1843–1914), Irish physician and politician John Little (MP) for City of London
Sports John Little (American football) (1947–1997), American football player John Little (basketball) (born 1984), American basketball player John Little (cricketer) (1927–2004), New Zealand cricketer John Little (footballer) (1930–2017), Canadian-born Scottish footballer
Other people John Little (academic) (1928–2024), American academic and operations researcher John C. Little (1874–1957), British trade unionist John H. Little (born 1941), superintendent of Wentworth Military Academy John N. Little, president and co-founder of The MathWorks John R. Little (born 1955), dark fiction writer John Little (American painter) (1907–1984), American artist John Little (Canadian painter) (1928–2024), Canadian artist John Little (writer) (born 1960), Bruce Lee scholar, bodybuilding/conditioning author, head of the film company JJL Enterprises LLC John B. Little (radiobiologist) (1929–2020), American radiobiologist John B. Little (mathematician) (born 1956), American mathematician and historian of mathematics
Commercial John Little (department store), a retail chain in Singapore
See also Little John, a member of Robin Hood's Merry Men Jack Little (disambiguation) Jonathan Little (born 1984), American poker player