Route 0, or Highway 0, may refer to routes in the following countries:

Belgium R0 motorway (Belgium), the ring road around Brussels

Czech Republic D0 motorway (Czech Republic), bypassing Prague

Hungary M0 motorway (Hungary), bypassing Budapest

Numbered streets 0 Avenue in British Columbia, Canada

Future highways Bucharest Ring Motorway, in Romania, when constructed, will be numbered A0.

Fictional Highway 0 from Jet Set Radio Future Interstate 0 from I-0 Route 0 from Kentucky Route Zero Highway Zero, a novel by Billy Lawrence

See also U.S. Route 2, the highway carrying the designation assigned to avoid a U.S. Route 0