Iliopoulos () is a Greek surname. Notable people with the surname include:

Dinos Iliopoulos (1915–2001), actor and film director Giannis Iliopoulos (born 1979), basketball player John Iliopoulos (born 1940), theoretical physicist Marios Iliopoulos (born 1969), heavy metal guitarist Vasileios Iliopoulos (born 1988), Greek tennis player