Lady Thompson may refer to:
Annie Thompson (née Affleck) (1845–1913), wife of the Prime Minister of Canada Ann Thompson (née Potts) (1869–1946), wife of Luke Thompson (politician) Kate Fanny Thompson (1825–1904), married name of English composer Kate Loder Lady Gwen Thompson, pseudonym of author Phyllis Thompson (née Healy) (1928–1986)