James Sweeney may refer to:
James Johnson Sweeney (1900–1986), museum curator James Joseph Sweeney (1898–1968), American, Roman Catholic bishop James Sweeney (film editor) (1901–1957), American film editor James Sweeney (Medal of Honor) (1845–1931), Union Army soldier during the American Civil War James Sweeney (filmmaker) (born 1990), American screenwriter, director, and actor James G. Sweeney (1877–1917), Nevada attorney general and justice of the Supreme Court of Nevada James R. Sweeney II (born 1961), American attorney James M. Sweeney (fl. 1960s–2010s), healthcare entrepreneur James Sweeney (architect) (1868–1919), American architect James Monroe Sweeney (1892–1950), American baseball umpire
See also Jim Sweeney (disambiguation) John James Sweeney (born 1927), Pennsylvania politician