Route 270 or Highway 270 may refer to:
Canada Manitoba Provincial Road 270 Prince Edward Island Route 270
Japan Japan National Route 270
United Kingdom B270 road
United States Interstate 270 (multiple highways) U.S. Route 270 California State Route 270 Florida State Road 270 (former) Georgia State Route 270 Hawaii Route 270 Kentucky Route 270 Maryland Route 270 Minnesota State Highway 270 New York State Route 270 Oklahoma State Highway 270 Pennsylvania Route 270 (former) Tennessee State Route 270 Texas State Highway 270 (former) Utah State Route 270 Virginia State Route 270 Washington State Route 270 West Virginia Route 270 Wyoming Highway 270