Francese is an Italian surname meaning "French". Notable people with this surname include:
Angela Francese (1950–2025), Italian politician Antonio Francese (1899–1979), Uruguayan Army general and politician of Italian descent Mario Francese (1925–1979), Italian crime reporter Paula Francese, American politician Peter Francese (born 1941), American demographic trends expert and writer of Italian descent
See also Francese Litchfield Turnbull (1844–1927), an American female novelist Chicken Francese, an Italian-American chicken dish Franzese, a similar Italian surname