William Culbertson may refer to:
William Culbertson (businessman), U.S. businessman from Indiana William Constantine Culbertson (1825–1906), U.S. Representative from Pennsylvania William Wirt Culbertson (1835–1911), U.S. Representative from Kentucky William Smith Culbertson (1884–1966), U.S. Ambassador to Romania and Chile William Culbertson III (1905–1971), fifth President of the Moody Bible Institute in Chicago
See also William Louis Culberson, lichenologist