Erwin Panofsky (1892–1968) was a German art historian who worked in the U.S.

Panofsky may also refer to:

Panofsky Prize, awarded in the field of particle physics

People with the surname Aaron Panofsky, American sociologist Dora Panofsky (1885-1965), German-American art historian Wolfgang K. H. Panofsky, German-American physicist

See also Panovsky, a rural locality in Vladimir Oblast, Russia