DPT may refer to:
Science and medicine Dpt (unit) (dioptre/diopter), most commonly a unit measuring refraction and power in a lens or curved mirror Deep pressure therapy, a sensory integration therapy Dermatopontin, a human extracellular matrix protein Dipropyltryptamine, a psychedelic tryptamine DPT vaccine, vaccine against diphtheria, pertussis and tetanus, also referred as DTP Doctor of Physical Therapy Distributed Processing Technology Dynamic Packet Transport
Politics Democratic Party of Turkmenistan Democratic peace theory, in political science Druk Phuensum Tshogpa, a political party in Bhutan
Entertainment Dumbarton People's Theatre, a Scottish theatre group Dirty Pretty Things (band), an English band founded in 2005 Dirty Pretty Things (film), a 2002 British drama
Transportation DPT, the National Rail station code for Devonport railway station, Devon, England Dublin Port Tunnel
Other State Planning Organization (), former government body in Turkey A department