William Creighton may refer to:
William Creighton Jr. (1778–1851), attorney, banker and legislator in Ohio William Black Creighton (1864–1946), Canadian social reformer William Steel Creighton (1902–1973), American myrmecologist and taxonomist William Creighton (bishop) (1909–1987), bishop of the Diocese of Washington William Creighton (rally driver) (born 1997), Irish rally driver