George Guthrie may refer to:
George H. Guthrie (born 1959), professor at Union University George James Guthrie (1785–1856), English surgeon George W. Guthrie (1848–1917), mayor George Guthrie (hurdler) (1904–1972), American track and field athlete George Guthrie (songwriter) (1842–?), Newcastle upon Tyne songwriter
See also Guthrie (surname) Guthrie (disambiguation)