John Otis is the name of:
John Otis (Maine politician) (1801–1856), U.S. Representative from Maine John G. Otis (1838–1916), U.S. Representative from Kansas John Lord Otis (1827-1894), American Civil War officer and Massachusetts state senator and state representative
See also Johnny Otis, born Ioannis Alexandres Veliotes (1921–2012), American singer, musician, composer, bandleader, record producer and talent scout who discovered many who would become major stars