James Trimble may refer to:
James A. Trimble (1847–?), street car works, 218 East 28th St., New York James Travis Trimble Jr. (born 1932), United States federal judge James William Trimble (1894–1972), Member of the US House of Representatives Jim Trimble, American college football coach James Trimble (Canadian politician) (died 1885), Speaker of the British Columbia legislature James Trimble III (1925–1945), baseball player and U.S. Marine