James Hopkins may refer to:
Politicians James G. Hopkins (1801–1860), New York politician James C. Hopkins (lawyer) (1819–1877), legislator, lawyer, and judge of New York and Wisconsin James Herron Hopkins (1832–1904), American politician James Scott-Hopkins (1921–1995), British Conservative Party politician
Other James Frank Hopkins (1845–1913), Confederate Army volunteer and founder of the Sigma Nu fraternity at the VMI James Hopkins (footballer, born 1873) (1873–?), English association football player for Manchester United James Hopkins (footballer, born 1901) (1901–1943), Northern Irish association football player for Arsenal and Brighton James C. Hopkins (architect) (1873–1938), Massachusetts architect, partner in Kilham & Hopkins James C. Hopkins, Jr. (architect) (c. 1914–1998), his son, also architectural firm partner James I. Hopkins Jr. (1918–1951), American lieutenant colonel Jim Hopkins (born 1946), New Zealand TV personality Jimmy Hopkins, fictional character in the 2008 video game Bully