The Seattle Mariners' 2001 season was the 25th since the franchise's inception. Widely considered one of the greatest baseball teams of all time, they finished with a 116–46 record (.71605 win %), tying the major league record for wins in the modern era since 1901, set by the 1906 Chicago Cubs,The 1906 Cubs set the mark in a 152-game season and setting the record for wins by an American League team.

Of the 116 wins, 59 were by four or more runs, setting a record that was later broken by the 2022 and 2023 Los Angeles Dodgers, each with 60 such wins. They also led the majors in both runs scored and fewest runs allowed. The 2001 Mariners hold the record for the most Wins Above Replacement (WAR) by a team in a season in MLB history, with 50.4. Even the 1927 New York Yankees, often considered the greatest team of all time due to their elite "Murderers’ Row" lineup, fell short of the Mariners; they recorded 48.7 WAR, 1.7 less than the Mariners, the second-highest single-season total in MLB history.

On August 5, 2001, the Cleveland Indians accomplished a historic 12-run comeback, defeating the Seattle Mariners 15–14 in 11 innings, after trailing 14-2 in the 7th inning. This remarkable victory, known as the "Great Return," tied a major league record for the largest comeback in a game, featuring five runs with two outs in the ninth inning.

The 2001 season was also notable for the Major League debut of star Japanese outfielder Ichiro Suzuki, who led the league in batting average and won both the AL Rookie of the Year and the AL MVP awards. Additionally, the Mariners hosted their second All-Star Game on July 10.

Winning the American League West, the 2001 season marked the first time the Mariners reached the postseason in consecutive seasons. The team defeated the Cleveland Indians in the ALDS in five games, but fell to the New York Yankees in five games in the ALCS. They became the first team in MLB history to win 110 or more regular season games and fail to reach the World Series. They would later be joined in this regard by the 2022 Los Angeles Dodgers.

Despite the record-setting win total, the Mariners would not reach the postseason again until 2022, which was the longest active drought in the four major North American sports. They would also not win the AL West or return to the ALCS again until the 2025 season.

Offseason November 7, 2000: Scott Podsednik was signed as a free agent with the Seattle Mariners. November 18, 2000: Ichiro Suzuki was signed as a free agent with the Seattle Mariners. December 22, 2000: Bret Boone was signed as a free agent with the Seattle Mariners.

Regular season

Roster 2001 Seattle Mariners Roster Pitchers Catchers

Infielders Outfielders

Designated Hitter Manager

Coaches

Season standings

Detailed records Opponent Home Away Total Pct. AL East Baltimore Orioles 6–0 2–1 8–1 Boston Red Sox 2–1 4–2 6–3 New York Yankees 1–2 5–1 6–3 Tampa Bay Devil Rays 5–1 2–1 7–2 Toronto Blue Jays 3–3 3–0 6–3 17–7 16–5 33–12 AL Central Chicago White Sox 5–1 2–1 7–2 Cleveland Indians 2–1 3–1 5–2 Detroit Tigers 3–1 2–1 5–2 Kansas City Royals 1–2 5–1 6–3 Minnesota Twins 3–0 5–1 8–1 14–5 17–5 31–10 AL West Anaheim Angels 7–3 8–1 15–4 Oakland Athletics 5–4 5–5 10–9 Texas Rangers 8–2 7–3 15–5 20–9 20–9 40–18 NL West Arizona Diamondbacks 2–1 0–0 2–1 Colorado Rockies 0–0 2–1 2–1 Los Angeles Dodgers 0–0 2–1 2–1 San Diego Padres 2–1 2–1 4–2 San Francisco Giants 2–1 0–0 2–1 6–3 6–3 12–6

Record vs. opponents

Game log

|-style=background:#bfb | 1 || April 2 || Athletics || 5–4 || Rhodes (1–0) || Mecir (0–1) || Sasaki (1) || 45,911 || 1–0 || W1 |-style=background:#fbb | 2 || April 3 || Athletics || 1–5 || Zito (1–0) || Halama (0–1) || – || 27,212 || 1–1 || L1 |-style=background:#bfb | 3 || April 4 || Athletics || 10–2 || Sele (1–0) || Heredia (0–1) || – || 31,382 || 2–1 || W1 |-style=background:#bfb | 4 || April 6 || @ Rangers || 9–7 (10) || Rhodes (2–0) || Zimmerman (0–1) || Sasaki (2) || 34,684 || 3–1 || W2 |-style=background:#bfb | 5 || April 7 || @ Rangers || 6–5 || Franklin (1–0) || Davis (0–1) || Sasaki (3) || 41,651 || 4–1 || W3 |-style=background:#fbb | 6 || April 8 || @ Rangers || 4–5 || Venafro (1–0) || Paniagua (0–1) || Crabtree (2) || 44,306 || 4–2 || L1 |-style=background:#bfb | 7 || April 10 || @ Athletics || 5–1 || Halama (1–1) || Heredia (0–2) || Sasaki (4) || 14,880 || 5–2 || W1 |-style=background:#bfb | 8 || April 11 || @ Athletics || 3–0 || Sele (2–0) || Mecir (0–2) || Sasaki (5) || 16,652 || 6–2 || W2 |-style=background:#bfb | 9 || April 12 || @ Athletics || 7–3 || Moyer (1–0) || Hudson (1–1) || – || 15,414 || 7–2 || W3 |-style=background:#fbb | 10 || April 13 || @ Angels || 3–4 || Hasegawa (1–0) || Sasaki (0–1) || – || 31,087 || 7–3 || L1 |-style=background:#bfb | 11 || April 14 || @ Angels || 2–1 || García (1–0) || Valdez (0–1) || Sasaki (6) || 34,780 || 8–3 || W1 |-style=background:#bfb | 12 || April 15 || @ Angels || 7–5 || Paniagua (1–1) || Hasegawa (1–1) || Nelson (1) || 20,733 || 9–3 || W2 |-style=background:#bfb | 13 || April 16 || Rangers || 9–7 || Franklin (2–0) || Glynn (0–3) || – || 45,657 || 10–3 || W3 |-style=background:#bfb | 14 || April 17 || Rangers || 6–4 || Moyer (2–0) || Helling (0–3) || Sasaki (7) || 34,536 || 11–3 || W4 |-style=background:#fbb | 15 || April 18 || Rangers || 6–8 || Davis (2–1) || Tomko (0–1) || Zimmerman (1) || 48,823 || 11–4 || L1 |-style=background:#bfb | 16 || April 19 || Angels || 3–2 || García (2–0) || Valdez (0–2) || Sasaki (8) || 25,016 || 12–4 || W1 |-style=background:#bfb | 17 || April 20 || Angels || 4–1 || Halama (2–1) || Rapp (0–3) || Sasaki (9) || 39,274 || 13–4 || W2 |-style=background:#bfb | 18 || April 21 || Angels || 5–2 || Moyer (3–0) || Washburn (0–2) || Nelson (2) || 39,274 || 14–4 || W3 |-style=background:#bfb | 19 || April 22 || Angels || 5–0 || Sele (3–0) || Ortiz (2–2) || – || 44,192 || 15–4 || W4 |-style=background:#bfb | 20 || April 24 || @ Yankees || 7–5 || García (3–0) || Stanton (1–1) || Sasaki (10) || 29,522 || 16–4 || W5 |-style=background:#bfb | 21 || April 25 || @ Yankees || 7–5 || Charlton (1–0) || Pettitte (3–2) || Sasaki (11) || 23,684 || 17–4 || W6 |-style=background:#bfb | 22 || April 26 || @ Yankees || 7–3 || Moyer (4–0) || Mussina (1–3) || Rhodes (1) || 30,218 || 18–4 || W7 |-style=background:#bfb | 23 || April 27 || @ White Sox || 8–3 || Sele (4–0) || Baldwin (0–1) || Sasaki (12) || 16,276 || 19–4 || W8 |-style=background:#bfb | 24 || April 28 || @ White Sox || 8–5 || Tomko (1–1) || Biddle (1–1) || Sasaki (13) || 25,542 || 20–4 || W9 |-style=background:#fbb | 25 || April 29 || @ White Sox || 1–2 (14) || Glover (2–1) || Franklin (2–1) || – || 25,442 || 20–5 || L1

|-style=background:#fbb | 26 || May 1 || Red Sox || 0–2 || Martínez (3–0) || Halama (2–2) || Arrojo (4) || 36,642 || 20–6 || L2 |-style=background:#bfb | 27 || May 2 || Red Sox || 5–1 || Sele (5–0) || Nomo (3–2) || – || 40,170 || 21–6 || W1 |-style=background:#bfb | 28 || May 3 || Red Sox || 10–3 || Moyer (5–0) || Castillo (3–2) || – || 32,513 || 22–6 || W2 |-style=background:#fbb | 29 || May 4 || Blue Jays || 3–8 || Parris (2–2) || Abott (0–1) || – || 42,284 || 22–7 || L1 |-style=background:#bfb | 30 || May 5 || Blue Jays || 7–5 || Rhodes (3–0) || Borbón (0–2) || Sasaki (14) || 42,894 || 23–7 || W1 |-style=background:#fbb | 31 || May 6 || Blue Jays || 3–11 || Carpenter (3–1) || Halama (2–3) || – || 45,080 || 23–8 || L1 |-style=background:#fbb | 32 || May 8 || @ Red Sox || 4–12 || Nomo (4–2) || Moyer (5–1) || – || 32,941 || 23–9 || L2 |-style=background:#bfb | 33 || May 9 || @ Red Sox || 10–5 || Nelson (1–0) || Arrojo (1–1) || Sasaki (15) || 31,616 || 24–9 || W1 |-style=background:#bfb | 34 || May 10 || @ Red Sox || 5–2 || Halama (3–3) || Ohka (2–2) || Sasaki (16) || 31,428 || 25–9 || W2 |-style=background:#bfb | 35 || May 11 || @ Blue Jays || 7–2 || Abbott (1–1) || Hamilton (1–2) || – || 20,279 || 26–9 || W3 |-style=background:#bfb | 36 || May 12 || @ Blue Jays || 11–7 || Tomko (2–1) || Escobar (0–1) || – || 24,908 || 27–9 || W4 |-style=background:#bfb | 37 || May 13 || @ Blue Jays || 7–5 || Moyer (6–1) || Loaiza (4–4) || Sasaki (17) || 20,624 || 28–9 || W5 |-style=background:#bfb | 38 || May 15 || White Sox || 4–3 || Nelson (2–0) || Howry (2–1) || Paniagua (1) || 31,096 || 29–9 || W6 |-style=background:#bfb | 39 || May 16 || White Sox || 7–2 || Abbott (2–1) || Biddle (1–3) || Paniagua (2) || 33,748 || 30–9 || W7 |-style=background:#bfb | 40 || May 17 || White Sox || 5–1 || García (4–0) || Wells (3–4) || Nelson (3) || 43,510 || 31–9 || W8 |-style=background:#fbb | 41 || May 18 || Yankees || 10–14 || Mendoza (3–1) || Halama (3–4) || – || 45,794 || 31–10 || L1 |-style=background:#fbb | 42 || May 19 || Yankees || 1–2 (10) || Stanton (4–1) || Sasaki (0–2) || Rivera (12) || 45,880 || 31–11 || L2 |-style=background:#bfb | 43 || May 20 || Yankees || 6–2 || Sele (6–0) || Clemens (4–1) || – || 45,953 || 32–11 || W1 |-style=background:#fbb | 44 || May 22 || @ Twins || 11–12 || Wells (4–1) || Abbott (2–2) || – || 29,005 || 32–12 || L1 |-style=background:#bfb | 45 || May 23 || @ Twins || 5–4 || Rhodes (4–0) || Carrasco (2–1) || Sasaki (18) || 26,605 || 33–12 || W1 |-style=background:#bfb | 46 || May 25 || @ Royals || 9–6 || Franklin (3–1) || Grimsley (0–2) || Sasaki (19) || 17,555 || 34–12 || W2 |-style=background:#bfb | 47 || May 26 || @ Royals || 7–2 || Sele (2–0) || Meadows (1–6) || – || 21,368 || 35–12 || W3 |-style=background:#bfb | 48 || May 27 || @ Royals || 5–4 || Charlton (7–0) || Santiago (2–2) || – || 19,524 || 36–12 || W4 |-style=background:#bfb | 49 || May 28 || @ Royals || 13–3 || Abbott (3–2) || Durbin (3–3) || – || 20,142 || 37–12 || W5 |-style=background:#bfb | 50 || May 29 || Orioles || 3–2 || García (5–0) || Roberts (5–4) || Sasaki (20) || 30,413 || 38–12 || W6 |-style=background:#bfb | 51 || May 30 || Orioles || 12–5 || Halama (4–4) || Johnson (4–3) || – || 34,757 || 39–12 || W7 |-style=background:#bfb | 52 || May 31 || Orioles || 2–1 || Sele (8–0) || Mercedes (1–7) || Sasaki (21) || 37,612 || 40–12 || W8

|-style=background:#bfb | 53 || June 1 || Devil Rays || 8–4 || Moyer (7–1) || Rekar (0–7) || Nelson (4) || 41,094 || 41–12 || W9 |-style=background:#bfb | 54 || June 2 || Devil Rays || 7–4 || Abbott (4–2) || Rupe (2–5) || Sasaki (22) || 45,473 || 42–12 || W10 |-style=background:#bfb | 55 || June 3 || Devil Rays || 8–4 || García (6–0) || Sturtze (2–5) || Sasaki (23) || 45,390 || 43–12 || W11 |-style=background:#bfb | 56 || June 4 || Rangers || 11–6 || Franklin (4–1) || Venafro (1–2) || – || 45,812 || 44–12 || W12 |-style=background:#bfb | 57 || June 5 || Rangers || 5–4 || Paniagua (2–1) || Smart (1–1) || Sasaki (24) || 44,853 || 45–12 || W13 |-style=background:#bfb | 58 || June 6 || Rangers || 7–3 || Moyer (8–1) || Oliver (4–2) || – || 45,754 || 46–12 || W14 |-style=background:#bfb | 59 || June 8 || Padres || 7–1 || Abbott (5–2) || Jarvis (3–6) || – || 45,293 || 47–12 || W15 |-style=background:#fbb | 60 || June 9 || Padres || 3–6 || Jones (3–8) || García (6–1) || Hoffman (12) || 45,322 || 47–13 || L1 |-style=background:#bfb | 61 || June 10 || Padres || 8–1 || Halama (5–4) || Loewer (0–1) || – || 45,418 || 48–13 || W1 |-style=background:#bfb | 62 || June 12 || @ Rockies || 10–9 || Fuentes (1–0) || Acevedo (0–1) || Sasaki (25) || 41,263 || 49–13 || W2 |-style=background:#bbb | – || June 13 || @ Rockies ||colspan=7| Postponed (rain); rescheduled June 14 (game 1) |-style=background:#fbb | 63 || June 14 (1) || @ Rockies || 2–8 || Chacón (4–3) || Moyer (8–2) || – || 45,261 || 49–14 || L1 |-style=background:#bfb | 64 || June 14 (2) || @ Rockies || 5–1 || Abbott (6–2) || Astacio (5–7) || – || 37,048 || 50–14 || W1 |-style=background:#bfb | 65 || June 15 || @ Padres || 5–1 || García (7–1) || Jones (3–9) || – || 60,918 || 51–14 || W2 |-style=background:#bfb | 66 || June 16 || @ Padres || 9–2 || Halama (6–4) || Loewer (0–2) || – || 61,065 || 52–14 || W3 |-style=background:#fbb