Painkiller or analgesic is a group of drugs.

Painkillers or pain killer may also refer to:

Games Painkiller (video game), a 2004 first-person shooter for the PC and Xbox Painkiller: Resurrection, an expansion pack for the 2004 game Painkiller: Hell & Damnation, a remake of the 2004 game

Music

Bands Painkiller (band), a band led by John Zorn and Bill Laswell

Albums Pain Killer (Energy Orchard album), 1995 Pain Killer (Krokus album), 1978 Pain Killer (Little Big Town album), 2014 Pain Killer (Moumoon album), 2013 Painkiller (Jim Bianco album), 2006 Painkiller (Judas Priest album), 1990 Painkiller, a 1992 album by Sue Ann Carwell Painkiller, a 2012 re-release edition of the EP Russian Roulette, or the song Painkillers (EP), a 1993 EP by Babes in Toyland

Songs "Pain Killer" (Iceage song), 2018 "Painkillerr" a song by Polish band Mech "Pain Killer" (Little Big Town song), 2015 "Pain Killer" (Turin Brakes song), 2003 "Painkiller" (Freestylers song), 2006 "Painkiller" (Jason Derulo song), 2015 "Painkiller" (Judas Priest song), 1990 "Painkiller" (Ruel song), 2019 "Painkiller" (Three Days Grace song), 2014 "Painkiller", a song by Blackbear from In Loving Memory "Painkiller", a song by Ted Nugent from Little Miss Dangerous "Painkiller", a song by Depeche Mode, the B-side of "Barrel of a Gun" "Painkiller", a song by Dreamers from This Album Does Not Exist "Painkiller", a song by Halestorm from Vicious "Painkiller", a song by Death from The Sound of Perseverance

Television Painkiller (TV series), a 2023 American drama limited series "Painkiller" (Black Lightning episode) Painkiller (Arrowverse)

Other uses Painkiller (cocktail), a rum cocktail Painkiller (comics), a DC Comics supervillain Painkiller (magazine), a Chinese heavy-metal music magazine The Painkiller (play), by Sean Foley, adapted from Francis Veber's Le Contract Painkiller, a 2011 short film starring Benedict Wong Painkillers (film), a 2018 film directed by Roxy Shih

See also "Painkillr", song by Erika Jayne