1B may refer to:
Science and technology Alpha-1B adrenergic receptor Arginine vasopressin receptor 1B Interferon beta-1b Melatonin receptor 1B The ASCII hexadecimal code for the escape character 1b as one billion
Sport First baseman Single (baseball)
Transport Axle arrangement on steam locomotives corresponding to a 2-4-0 wheel arrangement GCR Class 1B, a class of British 2-6-4T steam locomotive National Highway 1B (India, old numbering)
See also B1 (disambiguation) Billion