Siege of Antioch may refer to: Siege of Antioch (51 BC) by the Parthians Siege of Antioch (253) by the Sassanid Persians Siege of Antioch (260) by the Sassanid Persians by the Sassanid Persians Siege of Antioch (968–969) by the Byzantines Siege of Antioch (970–971) by the Fatimids Siege of Antioch (1084–1085) by the Seljuks Siege of Antioch (1097–1098) by the Crusaders Siège d'Antioche, French poem about the siege of 1098 Siege of Antioch (1268) by the Mamelukes