DXR may refer to:

DXR, a class of locomotives in New Zealand Danbury Municipal Airport (IATA code), Danbury, Connecticut Digital X-ray radiogrammetry, a method for measuring bone mineral density Doxorubicin, an anthracycline antibiotic used in cancer chemotherapy DXP reductoisomerase, an enzyme DirectX Raytracing, a computer graphics interface for real-time raytracing Drivex, a Spanish auto racing team