Othniel is the name of the first of the Biblical Judges. It can also be a given name. Notable people with the given name include:
Othniel Dossevi (born 1947), Togolese footballer Othniel Looker (1757–1845), American politician from Ohio and member of the Democratic-Republican Party. Briefly fifth Governor of Ohio Othniel Charles Marsh (1831–1899), American paleontologist Othniel Tripp (1826–?), American sailor Othniel Wienges (1924–2013), American horse breeder and politician
See also Othniel Looker House, registered historic building in Harrison, Ohio