USS Picket may refer to the following ships of the United States Navy:
USS Picket, bought 1862, headquarters of General Burnside during the Battle of Roanoke Island. , completed 15 April 1942 by Marietta Manufacturing Co., Point Pleasant, West Virginia , laid down 28 March 1945 as SS James F. Harrell by J. A. Jones Construction Co., Panama City, Florida
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