Sancti-Spíritus is a municipality in the province of Badajoz, Extremadura, Spain. According to the 2014 census,Instituto Nacional de Estadística (INE) the municipality has a population of 222 inhabitants.

A great part of the town's municipal term is submerged under the La Serena Reservoir, one of the largest in Spain.La Serena, la mayor bolsa de agua de España (El País)

See also La Serena List of municipalities in Badajoz

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