Guice is a surname. Notable people with the surname include:
Daniel Guice (1924–2017), American lawyer and politician Daniel Guice Jr. (born 1953), American businessman and politician Derrius Guice (born 1997), American football player Jackson Guice (1961–2025), American comics artist Jeffrey Guice (born 1959), American politician John T. Guice (1923–2001), United States Air Force officer Les Guice (born 1954), American university president
See also Google Guice Peter Guice Memorial Bridge