Derr is a surname. Notable people with the surname include:
Allen Derr (1928–2013), American lawyer A. M. Derr (1903–1970), American politician from Idaho E.B. Derr (1891 – 1974), American actor John W. Derr (born 1941), former Maryland State Senator Kenneth T. Derr, American businessman Zac Derr, American football placekicker Richard Derr (1918–1992), American film and television actor Jill Mulvay Derr (born 1948), American history professor Manuela Derr (born 1971), retired East German sprinter
See also Temple of Derr, Ancient Egyptian temple