The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.
See also Hepatitis C alternative reading frame stem-loop Hepatitis C virus 3'X element Hepatitis C virus stem-loop VII Hepatitis C stem-loop IV Hepatitis C
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