John Kane may refer to:
Entertainment John Kane (actor) (1746–1799), Irish actor and comedian John Kane (artist) (1860–1934), Scottish-born American painter John Kane (writer) (born 1945), British actor and writer
Law John L. Kane Jr. (born 1937), U.S. federal judge M. John Kane IV, Oklahoma Supreme Court Justice
Military John Kane (Medal of Honor), American soldier who fought in the American Civil War John R. Kane (1907–1996), American aviator and Medal of Honor recipient
Politics John I. Kane, American politician, Pennsylvania State Senator, and trade unionist John K. Kane (1795–1858), American politician John Kane (trade unionist) (1819–1876), British trade unionist Jock Kane (John Kane, 1921–2013), British intelligence agency officer and GCHQ whistleblower John Kane (politician), American politician, Oklahoma State House Representative
Sports John Kane (outfielder) (1882–1934), American baseball outfielder for the Cubs and Reds John Kane (infielder) (1900–1956), American baseball infielder for the Chicago White Sox John Kane (footballer, born 1960), English football player John Kane (footballer, born 1987), Scottish football player
Other John M. Kane, American psychiatrist John Innes Kane, American explorer, scientist and philanthropist
See also Jonny Kane (born 1973), British racing driver Jack Kane (1908–1988), Australian politician John Cain (disambiguation) John Caine (disambiguation)