He and She may refer to:

He and She (album), by Wynton Marsalis He & She, a 1967 American TV sitcom starring Richard Benjamin and Paula Prentiss L'assoluto naturale, Italian film internationally released as He and She He and She (play), a 1920 play by Rachel Crothers

See also He-she, or shemale She/he, the gender-independent third person pronoun, in couplet form She and He (1963 film), a Japanese film She & Him, an American musical duo Him & Her, a British television show Her & Him, an adult film His and Hers (disambiguation) He, She and It, 1991 novel She (disambiguation) He (disambiguation)