Abruzzi, a region of southern Italy.

Abruzzi may also refer to:

Places Abruzzi Glacier in northern Pakistan Abruzzi Ridge, Mount Saint Elias, Canada Abruzzi Spur, K2, Pakistan Abruzzi e Molise, the formerly combined region of Abruzzo and Molise

Other uses Duke of Abruzzi's Free-tailed Bat Luigi Amedeo, Duke of the Abruzzi (1873–1933), member of the Italian royal family and noted explorer John Abruzzi, a fictional character from the 2005 series Prison Break Panoz Abruzzi, a 2011 American sports car

See also Abbruzzi, an alternate spelling of the surname