Clijsters is a surname. Notable people with the surname include:
(born 1950), Belgian banker and chief executive Lei Clijsters (1956–2009), Belgian football player (1962–2005), Belgian artist and poet Kim Clijsters (born 1983), Belgian tennis player and oldest daughter of Lei Clijsters Elke Clijsters (born 1985), Belgian tennis player and youngest daughter of Lei Clijsters