S50 may refer to:
Automobiles BMW S50, an automobile engine Changan Ruixing S50, a Chinese MPV Daihatsu New Line (S50), a Japanese pickup truck Forthing Jingyi S50, a Chinese sedan Levdeo S50, a Chinese SUV Prince Skyline (S50), a Japanese sedan Suzuki Boulevard S50 a Japanese motorcycle Toyota Crown (S50), a Japanese luxury car Weiwang S50, a Chinese SUV
Aviation Auburn Municipal Airport (Washington), in King County, Washington, United States Blériot-SPAD S.50, a French biplane airliner Letov Š-50, a prototype Czechoslovak military aircraft SIAI S.50, an Italian biplane fighter Sikorsky S-50, an American helicopter
Electronics Canon PowerShot S50, a digital camera Cat S50, a mobile phone Nikon Coolpix S50, a digital camera Pentax Optio S50, a digital camera Roland S-50, a sampling keyboard Sirius S50, a satellite radio receiver ThinkCentre S50, a personal computer
Naval vessels , a submarine of the Royal Navy , a torpedo boat of the Imperial German Navy , a submarine of the United States Navy
Rail S50 (RER Fribourg), an S-Bahn line in Switzerland S50 (TILO), a rail service between Ticino, Switzerland, and Lombardy, Italy S50, a line of Vienna S-Bahn in Austria
Other uses S-50 (Manhattan Project), a uranium enrichment effort 5th Ring Road, an expressway in Beijing, China Expressway S50 (Poland) S50: Do not mix with ... (to be specified by the manufacturer), a safety phrase Toyota S50, a Toyota S transmission