Hufnagel (literally "hoof nail", metonymic occupational name for a farrier) is a surname. Notable people with the surname include:
Charles A. Hufnagel (1916–1989), American surgeon Johann Siegfried Hufnagel (1724–1795), German parson John Hufnagel (born 1951), Canadian football player, coach, and executive Kevin Hufnagel, American musician Klaus Hufnagel (born 1955), East German track and field athlete Leon Hufnagel (1893–1933), Polish astrophysicist Tibor Hufnágel (born 1991), Hungarian sprint canoeist Yanni Hufnagel (born 1982), American college basketball coach
See also Hufnagle