A54 may refer to:

Roads A54 road (England), a road connecting Chester and Buxton A54 motorway (France), a road connecting Salon-de-Provence and Nîmes A54 motorway (Italy), a ring road around Pavia A-54 freeway (Spain), a road connecting Santiago de Compostela and the N-550, N-634 and N-547 A54 motorway (Belgium), a road connecting Charleroi and E19

Other Agent A-54, a German double agent during World War II Old Indian Defense, Encyclopaedia of Chess Openings code Fiat A.54, a seven-cylinder, air-cooled radial engine developed in Italy in the 1930s as a powerplant for aircraft , a 1968 Indian Navy submarine tender ship Kanehana Station in Hokkaidō, Japan Samsung Galaxy A54 5G, an Android smartphone by Samsung Electronics