Esco or ESCO may refer to:
Places Esco, Kentucky, an unincorporated community in the US Escó, a village in Spain Escos, a commune in France
Organizations Ulefos Esco, a Norwegian valve and hydrant manufacturer Energy service company or energy savings company (ESCO or ESCo) ESCO Corporation, a manufacturer of engineered metal parts and components ESCO Foundation for Palestine, a private family foundation set up in 1940 Esco (Singaporean company) that develops, manufactures, and sells products and services for laboratories Estonian Shipping Company, a Soviet Union- (and later Estonia-) based shipping company Esco Trading, an arcade game company founded by Hayao Nakayama in 1967 and purchased by Sega in 1979
Other uses Esco (name) ESCO - European Skills, Competences, Qualifications and Occupations, a multilingual classification of identifies and categorises skills, competences, qualifications and occupations relevant for the EU labour market and education eSCO, a Bluetooth protocol for transmitting voice data ESCO1, or establishment of sister chromatid cohesion N-acetyltransferase 1, a protein that in humans is encoded by the ESCO1 gene ESCO2, an enzyme that in humans is encoded by the ESCO2 gene
See also Escondido, California, a city in California, US