LSG can refer to:
Organizations LSG Group, an aviation services company League of Saint George, a far right group Ligo de Seksemdiversaj Geesperantistoj, LGBTQ Esperantist organization Louisiana State Guard, the state defense force of Louisiana Lucknow Super Giants, an Indian cricket franchise
Music LSG (band), an R&B group L.S.G., a techno-trance project by Oliver Lieb
Science Laparoscopic sleeve gastrectomy, a surgical weight-loss procedure Virgo Supercluster, the Local Supercluster of galaxies
Other Loss of strength gradient, used in the context of military might; a theory that strength declines as distance increases Landing Ship Gantry, a US Navy type ship