FL2, FL-2, or similar may refer to: FL2 (Lazio regional railways) Florida State Road 2, two east–west highways in the U.S. state of Florida Florida's 2nd congressional district, a congressional district in the U.S. state of Florida Food & Liquor II, the fourth album by American conscious rapper Lupe Fiasco Football League Two, the third-highest division of The Football League, and fourth-highest division overall in the English football league system Football League 2 (Greece), the third highest professional football league in Greece A model of the Chinese Silkworm missile Fidgetin-like 2, a human enzyme