Humfrey is a given name and surname. Notable people with the name include:

Given name Humfrey Malins (born 1945), British Conservative politician Humfry Payne (1902–1936), English archaeologist

Surname Chris Humfrey, Australian zoologist and television personality Pelham Humfrey (1647–1674), English Restoration composer William Humfrey (died 1579), goldsmith and Assay Master to Queen Elizabeth I of England

See also Humphery, surname Humphrey, given name and surname Humphry, given name and surname