Aspera may refer to:

Music Aspera (band), an American indie rock band (a)spera, a 2009 album by Mirah Above Symmetry, a Norwegian progressive metal band originally known as Aspera "Aspera", the lead track from We Will Become Like Birds by Erin McKeown

Science Aspera European Astroparticle network, a physics organization

Technology Aspera (company) a file transfer software company Analyzer of Space Plasmas and Energetic Atoms, an instrument package on the Mars Express and Venus Express spacecraft Automatic Space Plasma Experiment with Rotating Analyzer, an instrument on board the Phobos 2 spacecraft

Biology and Anatomy Ulmus 'Aspera', a kind of elm tree Aspera, a nomen superfluum for the Rubiaceae genus Galium Aspera (coral), a genus of coral H. aspera (disambiguation), several species of plants Linea aspera, a bone structure in human anatomy

Other Per aspera ad astra, a Latin phrase